For example, if the frequency of fractures

Osteoporosis can also result from deficiency of vitamin D, which is

common among institutional older men and can lead to

osteomalacia, secondary hyperparathyroidism, increased bone turnover

and bone loss . Loss of bone mass is accelerated (not stop) at

older men and women who have secondary hyperparathyroidism, in part

, because this condition leads to an increase in porosity and intrakortykalna

thinning crust that predispose to fractures hip. Excessive alcohol intake >> << (including said

) is an important

associated risk factor for osteoporosis in men. There is no proven treatment for osteoporosis in men, because

no relevant randomized controlled trials. Calcium supplements

are safe and can slow bone loss, at least in women. Vitamin D deficiency should be

suspects linked to the building or company and the elderly should be considered

(after excluding malabsorption) of daily vitamin D

supplements. Estimated efficiency 1 ,25-dihydroxy D

to treat osteoporosis in women, caused him to be approved in

Australia for the treatment of osteoporosis in men. Hypogonadism should be treated with

Testo sterone (which can increase bone mineral density

[ON] in eugonadal men, but only in short-term studies have been done). >> << Possible increased risk of prostate cancer associated with testosterone therapy

should be considered in any analysis of costs and benefits >>. << Several small short-term studies in men with idiopathic or secondary osteoporosis

suggest that bisphosphonates increase and decrease ABOUT

bone. Studies in women with primary osteoporosis, and animals

suggest that drugs such as alendronate and etidronat appear

best option at this time. However, as long safety Dana

limited, these drugs should be given with caution. Bisphosphonates may remain in bone indefinitely, Alendronate can cause irritation

stomach or esophagus, ulcers, and can etidronat

cause osteomalacia coordination with the introduction of a long time. Sodium fluoride

increases the IPC, but not bone strength and should not be used >> << osteoporosis in men and women. There is no evidence of favorable effects >> << anabolic steroids in men. The problem of osteoporosis and fractures in men, probably

growth. To use the drug in men based on research on women

not the long-term solution. Drug therapy for men should be

on the basis of efficacy, safety and quality of life in men. As

all measures in preventive medicine, potential drug therapy should be

safe because most people who are treated makes no benefits. For example >> << if the frequency of fractures of two to 100 people a year, and drugs

has 50% antifracture efficacy, in any year 98 men will be

with a broken or without treatment, you have to >> << fracture in any case, and in one, fracture will be prevented - 99 receive benefits no

. Obviously, treatment should be safe. Age-related hip fracture incidence in men with low IPC should be defined

promising, so we can determine the efficacy of the drug. For example, if the frequency of fractures of two to 100 people a year,

1260 men with hip fracture and 1260 management will be needed to identify >> << 50% reduced risk of drugs in three years of research. Smaller sample sizes

may be adequate if the high risk group with low baseline ABOUT lasix 60 mg iv

and fractures to work. Study end points, such as,

histomorfometrii, biochemical indices of bone turnover and biomechanical testing

bone biopsy can provide at least

explanation appropriate drugs for use in men. Associate Professor of Medicine, Austin 167: 412-415. .