Friday, February 24, 2012

Parathyroid hormone (teriparatide) stimulates the ...

If the doctor diagnosed osteoporosis, your doctor will likely recommend:


increase your exposure to sunlight Limited correct any deficiencies of vitamin D, or from additives


Your doctor may change or reduce some drugs, because they can cause osteoporosis. Corticosteroid preparations, for example. Prednisolone is used to treat many other diseases such as asthma and arthritis, can lead to osteoporosis and may reduce your dose. Osteoporosis drugs work by bone cells that break bone ineffective, leaving the cells form bone alone. This reduces the amount of bone lost, so that net income in bone density occurs over time.

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There are several types of drugs:


Bisphosphonates ryzedronat (trade name Actonel), alendronate (fosamaks), disodium etidronat (Didrocal) and zoledronovoyi acid (Aclasta). These drugs reduce the risk of fractures by increasing bone density and reducing bone turnover. On average, these drugs lead to increased bone density by about 4-8% in the spine and 1-3% in the hip during the first 3-4 years of treatment. In clinical trials involving people with osteoporosis, bisphosphonates have been shown to reduce the incidence of fractures of the spine by as much as 30 - 40%, and in the thigh as much as 30-50%. Bisphosphonates are the most studied drug for the treatment of men with osteoporosis. Quitting smoking and reducing excessive alcohol consumption are often recommended. Bisphosphonates have been shown to protect against development of osteoporosis in people taking corticosteroids (eg cortisone, prednisone) for other diseases. Bisphosphonates should first pill in the morning on an empty stomach with a glass of water. You must remain upright for half an hour after them and not eat or drink anything other that a half hours. In addition, calcium and oral bisphosphonates should be taken not less than two hours. Otherwise, the absorption can influence others. Side effects are generally small, but may include pain in swallowing, upper gastrointestinal tract and stomach. It is important that these drugs with recommended amount of water and remain upright for 30 minutes after taking the drug to avoid the rare complication of ulcers and erosions in the esophagus. Fosamax Plus is Foxamax of vitamin D. Actonel Combi is Actonel with calcium. Actonel Combi D is as Actonel with calcium and vitamin D. Aclasta is the new bisphosphonates in the form once a year, fifteen minute intravenous infusion. It should be administered by a doctor or nurse. Jaw osteonecrosis of the jaw Bisphosphonates osteonecrosis (bone death that means) was the most frequently reported in cancer patients with very high doses or zoledronat pamidronat. It is very rare in people taking bisphosphonates to treat osteoporosis, where doses (oral and intravenous) is much lower. This problem can be caused by the fact that tooth removed if the injury is related while getting a tooth or infection occurs after that. Patients should be aware of this potential side effects, especially if they have poor oral hygiene and is likely to face tooth. If you have poor oral hygiene and may require extraction, consider seeing a dentist before you start on bisphosphonates. For those who are already taking bisphosphonates, you should tell your dentist you are taking bisphosphonates if the tooth or implant is planned. Strontium ranelate (Protos) is a tool for prevention of fractures in post-menopausal lasix fluid pill women with osteoporosis. It has a dual effect - increase in bone formation and decreasing bone resorption. This reduces vertebral fractures by 50%, without vertebral fractures by 16% and reduces hip fractures by 19% >> << This once daily dose, taken as a powder mixed with water. It is best to take at bed time for at least 2 hours after food containing calcium products or antacids. Possible side effects: nausea, diarrhea, headache and skin irritation. Unusual side effect of clot in the vein (thrombosis), so if you feel pain or swelling in the legs or unusual or sudden shortness of breath, seek immediate medical attention. Very rare side effect of strontium ranelate is a drug hypersensitivity syndrome, which causes fever and / or rash and can affect other organs. Consult your doctor immediately if fever and / or rash occurs while taking this medicine. The active substance in Prolia, denosumab, is a monoclonal antibody. Monoclonal antibody is a type of protein, which was designed to recognize and provide a structure (called antigen) in the body >> << There is a specific antigen in the body responsible for the activation of cells involved in the destruction bone (they are called osteoclasts). Denosumab adds and blocking this antigen, and thereby reduces the formation and activity of osteoclasts. It reduces bone loss and maintains bone strength, making fractures would be unlikely. Denosumab given input because it works for a long time, you will not need another dose DenosumabP for 6 months. Estrogen therapy can prevent bone loss in post menopausal women and reduce the risk of fractures. However, because HRT was associated with a small relative increase in the frequency of cardiovascular disease (heart attack and stroke) and breast cancer is not recommended for managing the risk of fractures only, as it requires long-term use. HRT is suitable for short-term relief of symptoms of menopause (5 years) and may play a role in preventing bone mineral density loss in women these symptoms. Its use is most appropriate for women to 60. In men with low testosterone (hypogonadism), hormone therapy increases bone density. Raloksifen (trade name: Evista). This class of drugs is a way to either the same or opposite estrogen, depending on which body the drug acts on. In bone it acts like estrogen to reduce bone loss. Raloksifen reduces the incidence of spine fractures by 50%, but was not shown to reduce the risk of hip fractures without a backbone. Unlike HRT, raloksifen may worsen the symptoms of menopause. Raloksifen also showed reduced risk of invasive breast cancer in post menopausal women long-term therapy (more than 5 years) without increasing the risk of endometrial cancer. However, there is an increased risk of blood clots and fatal stroke. Increased risk of venous thrombosis (clotting), reported on raloksifen similar to that observed with HRT, so if you are immobilized for a long time your doctor will likely advise you to stop it. Parathyroid hormone (teriparatide) stimulates bone formation and increases bone density and strength. The density of the bones of the spine has been shown to increase to 10% in some people and in the study of postmenopausal women with fractures to the spine, showed reduction in the incidence of spinal (65%) and spinal (55%) fractures. Forteo is available in Australia for people with established osteoporosis who have had fractures when other drugs are considered unsuitable. Side effects include dizziness and leg cramps. How long should I take medication? Your bone density improves very slowly, especially in the hips, so that the effect of the drug may take many months to occur. Reducing the risk of fractures seen bisphosphonates and SERMs can be seen within 6 months to one year after beginning treatment. You may have to take medication in the long run. Your doctor may observe the effect of treatment, repeat DXA scans and other tests at various stages. To get maximum benefit from your prescription medication, it is important to take them as directed and for as long as your doctor prescribes. Unfortunately, many people stop treatment for 2 years, which is common with long-term medications. This means that you will not get full value from taking drugs. Approved by Osteoporosis Australia Medical Research Advisory Committee updated environment, July 6, 2011 10:55.


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